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The deafness associated with meniere syndrome begins with an inabili- ty to hear low-frequency sounds and later progresses to involve higher frequency sounds key concept objective to be familiar with the presentation of meniere syndrome although episodes of vertigo associated with meniere syndrome usually last from hours to a day order metoclopramide 10mg visa, deafness is constant after it develops generic 10 mg metoclopramide fast delivery.

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After the intrathecal use of methotrexate, the central nervous system toxicity which may occur can be classified as follows acute chemical arachnoiditis manifested by such symptoms as headache, back pain, nuchal rigidity, and fever; sub-acute myelopathy characterized by paraparesis paraplegia associated with involvement with one or more spinal nerve roots; chronic leukoencephalopathy manifested by confusion, irritability, somnolence, ataxia, dementia, seizures and coma.

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