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Avoid the use of anacin if you are allergic to anything in the medication; you are a child or teenager with influenza or chickenpox; you have bleeding problems such as hemophilia, von willebrand disease, or low blood platelets, or you have severe active bleeding; you have had a severe allergic reaction to aspirin, tartrazine, or a non-steroidal anti-inflammatory drug; or you are taking anticoagulants or methotrexate.

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Some products that may interact with this drug include diet pills appetite suppressants such as diethylpropion , drugs for attention deficit disorder such as atomoxetine, methylphenidate , apraclonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, a certain combination product dextromethorphan quinidine , levodopa, maprotiline, methyldopa, certain narcotic pain relievers such as fentanyl, meperidine, methadone, tapentadol , certain drugs for parkinson s disease such as entacapone, tolcapone , certain supplements such as tryptophan, tyramine , tetrabenazine, tricyclic antidepressants such as amitriptyline, doxepin , valbenazine.

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